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What is serapeptase?

Serapeptase is a proteolytic enzyme, i.e. it breaks down proteins into smaller components called amino acids. It is produced by a bacterium in the digestive tract of silkworms, which allows them to dissolve their cocoons.

The first observation of the anti-inflammatory effect of serapeptase was made in the United States in 1950, and a second observation was made in Japan when the enzyme was isolated from silkworms. As a result of the research, serapeptase has been named the most efficient proteolytic enzyme.

Since then many other benefits and uses of serapeptase have been discovered.


Among the benefits of serapeptase are the following:

  • May reduce inflammation
Serapeptase is mainly known for its anti-inflammatory effect.

In dentistry, this enzyme is used in procedures such as tooth extraction, pain reduction, jaw muscle spasms and reducing post-operative inflammation.

Serapeptase is proven to decrease the number of inflamed cells in the affected area.

Studies have shown and confirmed that serapeptase has effects that can be compared to painkillers or analgesics. In particular, serapeptase has been shown to be more effective than ibuprofen or corticosteroids, powerful drugs designed to cure severe inflammation.

In addition, the same study showed that serapeptase is much safer than painkillers.

  • Can reduce pain
Serapeptase can reduce pain, another symptom of inflammation, by inhibiting the compounds that induce it.

One study included 200 participants suffering from ear, nose and throat infections.

Following the administration of serapeptase, participants observed a significant reduction in inflammation and pain. Similarly, another study found that serapeptase can significantly reduce the intensity of pain following tooth extraction.

Another study showed that serapeptase can be successfully administered following dental surgery, but was less effective than corticosteroids.

  • Serapeptase may prevent infections
Serapeptase may reduce the risk of bacterial infection.

A biofilm to which a bacterium attaches forms a protective barrier to the group.

This biofilm acts as a protective wall against antibiotics, allowing the bacteria to grow rapidly and cause infection. Serapeptase stops the biofilm forming and improves the effectiveness of antibiotics.

Test tube studies showed that antibiotics were more effective when combined with serapeptase. In addition, serapeptase combined with antibiotics was effective in treating antibiotic-resistant infections.
  • Can dissolve blood clots
Serapeptase can successfully treat atherosclerosis, a condition in which plaque develops inside the arteries.

It is thought to destroy affected tissue and fibroma, a powerful protein formed in blood clots.

But this information has not yet been proven except by the personal experiences of a few people.

So more research is needed to confirm its role in dissolving blood clots.

  • May be beneficial in chronic respiratory conditions
Serapeptase may increase mucus clearance and reduce inflammation in the lungs in people with chronic respiratory conditions.

In a 4-week study, a random selection of 29 people with chronic bronchitis was made from a group of 29 people who were given a dose of 30 mg of serapeptase daily. The others were given the usual treatment. Bronchitis is a condition that manifests itself by coughing and difficulty in breathing, factors that lead to mucus production.

In people given serapeptase, mucus production decreased compared to those given only the usual treatment.



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