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Natural Factors BioCoenzymated™, Methyl folate, 1,000 mcg, Natural Factors, 60 tablets

Natural Factors
-34%
159,08 RON 104,99 RON

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Expiration Date: 08.2027

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BioCoenzymated Methylfolate: Efficient Methylation, Cardiovascular Health, Mental Balance, and Cellular Energy – Premium Support for Optimal Body Function

 

BioCoenzymated™ Methylfolate 1,000 mcg, from Natural Factors, is an advanced dietary supplement formulated with the most active form of folate(6S)-5-methyltetrahydrofolate (MTHF) – as a glucosamine salt (Quatrefolic®), synergistically paired with vitamin B12 in the form of methylcobalamin.

 

This innovative combination supports homocysteine metabolism, efficient methylation, red blood cell formation, normal development of the nervous system, and healthy brain function. Unlike synthetic folic acid, which requires multiple metabolic conversions to become active in the body, MTHF (methylfolate) is the biologically active form of folate, immediately available for cellular use.

 

As a result, it is ideal for individuals with MTHFR genetic mutations or other metabolic deficiencies that prevent the efficient conversion of folic acid into its active form. The combination with methylcobalamin – the active form of vitamin B12 – ensures comprehensive support for DNA synthesis, cell division, mental balance, and energy production.

Detailed Benefits of BioCoenzymated™ Methylfolate with B12 Methylcobalamin

🛡️ Supporting cellular methylation – an essential process for overall health

Methylation is a fundamental biochemical process that takes place in every cell of the body and influences numerous biological functions, including DNA and RNA synthesis, regulation of gene expression, detoxification of harmful compounds, and the formation of neurotransmitters.

✅ supports efficient methylation, essential for epigenetic balance
✅ provides support for liver detoxification and reduction of homocysteine accumulation
✅ supports the production of neurotransmitters that regulate mood

♻️ Reducing homocysteine levels – cardiovascular protection

Homocysteine is an amino acid naturally produced in the body, but in high concentrations it can become harmful, promoting vascular inflammation, atheromatous plaque formation, and increasing the risk of cardiovascular disease, stroke, and thrombosis. Active folate and vitamin B12 play an essential role in converting homocysteine into methionine.

✅ contributes to the normalization of homocysteine levels in the blood
✅ reduces vascular inflammation and the risk of coronary artery disease
✅ protects the health of the heart and circulatory system

Improving cognitive function and mental health

Folate and vitamin B12 in their active forms are essential for the synthesis and balance of brain neurotransmitters such as serotonin, dopamine, and norepinephrine. Deficiencies in methylfolate or methylcobalamin can lead to chronic depression, anxiety, irritability, and difficulties with concentration and memory.

✅ supports mental health and emotional well-being
✅ supports neurochemical synaptic transmission processes
✅ reduces the risk of depression, especially in individuals with MTHFR polymorphism

🧠 Support for pregnancy and healthy fetal development

Methylfolate is one of the most vital substances during pregnancy, as it is essential for cell division, fetal nervous system development, preventing neural tube defects, and normal placental formation and fetal vascularization. Unlike synthetic folic acid, methylfolate is directly available for cellular utilization.

✅ directly available for cellular use without intermediate enzymatic steps
✅ better absorbed and tolerated by women with MTHFR mutations
✅ provides superior neurodevelopmental protection during pregnancy

📈 Red blood cell formation and cellular energy support

Both folate and vitamin B12 are vital for DNA synthesis and erythrocyte production in the bone marrow. Deficiencies in these vitamins can cause megaloblastic anemia, severe fatigue, weakness, shortness of breath, and dizziness. Methylfolate and methylcobalamin contribute directly to energy metabolism.

✅ supports normal red blood cell formation
✅ helps prevent anemia associated with folate/B12 deficiencies
✅ supports increased daily energy levels and stamina

🌿 Support for liver detoxification and cellular health

Methylfolate is involved in the synthesis of glutathione – the body's most crucial intracellular antioxidant – by supporting the methionine-cysteine cycle. This helps neutralize free radicals and toxins, regulates inflammatory processes, and prevents cellular damage and genetic mutations.

✅ supports efficient liver detoxification
✅ contributes to maintaining cellular integrity and protecting DNA
✅ supports the reduction of systemic oxidative stress

BioCoenzymated™ Methylfolate from Natural Factors is a next-generation supplement designed for individuals seeking an efficient source of active folate and methylated vitamin B12 to support methylation, energy, cardiovascular health, as well as mental and cellular wellness. By combining Quatrefolic® technology with methylcobalamin, this formula provides rapid absorption, increased tolerance, and superior therapeutic efficacy.

Advantages

1,000 mcg active MTHF folate per tablet Fast-absorbing Quatrefolic® 50 mcg vitamin B12 methylcobalamin Supports methylation, homocysteine, and energy Brain, heart, and cellular health support
Supplement Facts
Serving Size: 1 tablet
  Amount Per Serving % DV
Folate (from (6S)-5-methyltetrahydrofolic acid (MTHF), glucosamine salt, Quatrefolic®) 1,700 mcg DFE (1,000 mcg folic acid) 425%
Vitamin B12 (methylcobalamin) 50 mcg 2,083%

Suggested Use

Chew or dissolve 1 tablet per day in the mouth before swallowing, or as directed by a health professional.

Advantages

1,000 mcg active MTHF folate per tablet Fast-absorbing Quatrefolic® 50 mcg vitamin B12 methylcobalamin Supports methylation, homocysteine, and energy Brain, heart, and cellular health support

Other Ingredients

Lactose, microcrystalline cellulose, croscarmellose sodium, †Farm Fresh Factors™, magnesium stearate (vegetable grade).
†Active Vegetables - organic kale, organic alfalfa, organic cilantro leaves, organic parsley, sea buckthorn, sprouted garlic, organic artichoke, organic black radish, organic dandelion, barley grass, pepper, organic celery seed, organic beetroot, organic tomato; Cruciferous Vegetables - a broad spectrum of fully active glucosinolates and myrosinase enzymes from wasabi rhizome (Wasabia japonica) and fresh freeze-dried sprouted broccoli, organic upland cress, daikon, red radish, organic cauliflower, organic cabbage, organic arugula, organic watercress leaves; Ultra Fruit Polyphenols - grape, pomegranate, strawberry, organic blueberry, raspberry, bilberry, cranberry, organic Indian gooseberry, schizandra fruit, red orange, organic acai fruit; Herbals and Botanicals - Theracurmin® curcumin, organic decaffeinated green tea extract, organic ginger rhizome, organic echinacea, organic oregano, organic peppermint, organic spearmint; Whole Plant Sea Vegetables - organic spirulina, organic chlorella, red algae, blue green algae, kelp.
Contains milk.
Contains no artificial colors, preservatives, or sweeteners; starch-free, wheat-free, gluten-free, yeast-free, soy-free, corn-free, egg-free, fish-free, shellfish-free, salt-free, tree nut-free, or GMOs.
Manufactured by Natural Factors to ensure safety and potency in accordance with the Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Warnings

As with any supplement, consult your health professional before use if you are pregnant, nursing, or trying to conceive, or if you are taking medications, have a medical condition, or anticipate surgery. Keep out of reach of children.
Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

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