Melatonin, 6 Hour Timed Release 750 mcg: Deep and Continuous Sleep, Circadian Rhythm Regulation and Nighttime Recovery – Controlled Release Formula for Stable Rest

Melatonin, 6 Hour Timed Release, 750 mcg, Life Extension is a dietary supplement designed to support physiological sleep through an intelligent approach: gradual melatonin release over approximately 6 hours. Melatonin is a hormone naturally produced by the pineal gland, with a central role in regulating circadian rhythm – the "biological clock" that coordinates the sleep-wake cycle, body temperature, certain hormone secretion and nighttime recovery processes. Normally, melatonin levels increase in the evening, signaling the body that it is time for rest, then gradually decrease toward morning.

Modern lifestyle can disrupt this flow: exposure to artificial light (especially screens), irregular schedule, travel with time zone changes, chronic stress or shift work can dysregulate circadian rhythm, causing difficulty falling asleep, fragmented sleep or nighttime awakenings. In addition, with aging, natural melatonin secretion tends to decrease, and sleep can become more superficial and less continuous. The Life Extension timed release formula is created precisely to better mimic the physiological curve of melatonin, offering support both for sleep onset and maintenance.

Through the intake of 750 mcg melatonin in a controlled release system, the product aims to support a smoother transition to sleep and more stable rest throughout the night, without sudden peaks and rapid drops. This feature differentiates it from immediate release forms, predominantly oriented toward falling asleep, offering a more complete solution for people who want more continuous sleep and sustained nighttime recovery.

Detailed Benefits of Melatonin, 6 Hour Timed Release (Life Extension)

 

• Supporting falling asleep through natural signaling of "night beginning"

Falling asleep is not just a matter of fatigue, but a neurobiological process in which the brain receives signals that the environment is safe and that it is the right time for rest. Melatonin acts as a "messenger of darkness," contributing to sleep initiation by synchronizing the internal clock with real time. When this signal is weak, sleep onset can become slow, with repeated turns in bed, active mind and difficulty "disconnecting."

Timed release melatonin can support:
✅ faster transition from alert state to relaxation state
✅ reducing the "window" of time until falling asleep when evening routine is disrupted
✅ installing more natural sleep, without the feeling of "forcing" the body
✅ supporting a calmer sleep onset during periods of stress or overstimulation

This effect is especially useful for people who feel that "sleep doesn't come" at the desired time, although they are tired.

 

• Maintaining sleep throughout the night through controlled release for 6 hours

Restful sleep doesn't just mean falling asleep, but staying asleep long enough to go through complete cycles (light sleep, deep sleep, REM). Nighttime awakenings or fragmented sleep can reduce rest quality, even if the total number of hours seems sufficient. Here intervenes the major advantage of the Timed Release formula: gradual release maintains more stable support for nighttime rhythm, better mimicking the natural profile of melatonin.

This progressive release can contribute to:
✅ more continuous sleep, with fewer interruptions throughout the night
✅ supporting sleep stability in the second half of the night, when some people wake up frequently
✅ reducing the feeling of "superficial sleep" and awakenings to minor noises
✅ a more balanced awakening, with the perception of a "complete" night

For many, maintaining sleep is the main challenge, and a timed release formula is a logical choice when the problem is not just falling asleep.

 

• Circadian rhythm regulation and supporting adaptation to irregular schedules

Circadian rhythm is a synchronization system that functions optimally when sleep hours, light and meals are relatively constant. When schedule changes frequently (shift work, late bedtime, very early awakenings), the internal clock can "drift," and the body no longer knows exactly when to be alert and when to recover. Melatonin is one of the key tools through which the body adjusts this synchronization.

Supplementation can support:
✅ stabilizing sleep time when routine is variable
✅ easier re-entry into a desired schedule (for example, after weekend)
✅ reducing the impact of time zone shifts on sleep
✅ supporting adaptation to seasonal changes or periods with reduced exposure to natural light

Because the release is controlled, the nighttime signal can be perceived more coherently, which helps the body "understand" better that night should remain night.

 

• Supporting deep sleep and nighttime nervous system recovery

Sleep is the moment when the body enters a repair mode: the nervous system reduces its hyperactivity, memory is consolidated, tissues are regenerated and certain mediators involved in stress are balanced. When sleep is interrupted, these processes can be incomplete, and in the morning the feeling of "remaining fatigue" can appear.

Melatonin can contribute indirectly to:
✅ supporting deep sleep quality, associated with physical recovery
✅ balancing stress response through a more stable night
✅ diminishing the feeling of accumulated exhaustion when sleep is fragmented
✅ a clearer mental state the next day, through more efficient rest

This benefit is important for active people, who need the night to be a real recovery interval, not just a pause.

 

• Antioxidant support and nighttime protection against oxidative stress

Besides its circadian role, melatonin is also recognized for antioxidant activity, being involved in protecting cells against oxidative stress. Night is a period when the body "resets" part of its internal balances, and supporting an antioxidant environment can be relevant for tissue protection, especially in the context of chronic stress, fatigue and exposure to environmental factors.

Can support:
✅ cellular protection during periods of increased demand
✅ balance of repair mechanisms that occur during the night
✅ supporting recovery quality in the context of an intense lifestyle

This aspect complements the effect on sleep, offering a broader perspective on melatonin's role in nighttime physiology.

 

• Better rest quality for people who wake up during the night

There are people who fall asleep relatively easily, but wake up after 2-4 hours and then have difficulty falling back asleep, or wake up several times. In such cases, an immediate release formula may be insufficient, because its effect may decrease before the night ends. Timed Release is built precisely to support the nighttime "background."

Can contribute to:
✅ reducing recurring awakenings that fragment sleep
✅ maintaining the feeling of "connected" and more restful sleep
✅ improving sleep consistency from one night to another
✅ a more balanced morning, with less feeling of insufficient sleep

 

• Support for sleep hygiene through a more coherent nighttime signal

When sleep becomes more stable, it is easier to create a routine: the body anticipates bedtime, and the transition to rest becomes more natural. Timed release melatonin can function as a circadian "anchor," helping to consolidate healthy sleep habits.

Helps with:
✅ establishing a more predictable sleep rhythm
✅ supporting an evening routine with smoother transition
✅ reducing large variations from one night to another
✅ maintaining consistent rest, important for daily performance

Melatonin, 6 Hour Timed Release, 750 mcg, Life Extension is thus an option oriented toward complete sleep: it supports falling asleep, but especially sleep maintenance and circadian rhythm stability, through controlled release that more faithfully follows nighttime physiology.

 

 

Directions for Use

Read the entire label and follow directions carefully prior to use.
Take one (1) capsule 30 to 60 minutes before bedtime, or as recommended by a healthcare practitioner. 
Melatonin is naturally secreted by the pineal gland at night and should be taken at night for optimal results.





 

Supplement Facts
Serving Size: 1 Vegetarian Tablet
	Amount Per Capsule	% Daily Value
Melatonin	750 mcg	**
**Daily Value not established

 

Other Ingredients

Microcrystalline cellulose, hydroxypropyl methylcellulose, hydroxypropyl cellulose, aqueous coating (purified water, hydroxypropyl methylcellulose, glycerin), stearic acid, vegetable stearate, croscarmellose sodium, silica.

 

Warnings

Do not consume alcohol, drive or operate machinery after taking this product. 
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or nursing.  Keep tightly closed in a cool, dry place.