L-Methionine 500 mg: Hepatic Detox, Hair-Skin-Nails & Lipid Metabolism – Advanced Formula with B-6 for Methylation, Glutathione & Cellular Energy

L-Methionine 500 mg, Now Foods is a premium supplement based on a sulfur-containing essential amino acid, indispensable for methylation processes, glutathione synthesis and general metabolic balance. The formula combines L-Methionine (Free Form) 1 g (1,000 mg) per serving with Vitamin B-6 (from pyridoxine HCl) 20 mg (1176%), essential cofactor in sulfur amino acid metabolism (methionine-homocysteine-cysteine-taurine). Through S-adenosyl-methionine (SAMe), L-methionine fuels hundreds of methylation reactions involved in creatine production, membrane phospholipids, neurotransmitters and fine epigenetic regulation mechanisms. In parallel, the transsulfuration pathway converts methionine to cysteine – direct precursor of glutathione, the body's "master antioxidant," with central role in hepatic detoxification and cellular protection.

In an active life context, with increased metabolic demands and exposure to oxidative factors, L-methionine provides biochemical "building blocks" for an efficient liver, skin with supported cutaneous barrier, strengthened hair and nails, as well as a harmonized lipid profile within a balanced lifestyle.

Detailed Benefits of L-Methionine 500 mg (Now Foods)

• Advanced methylation and SAMe support

Methylation is a biochemical "language" that regulates synthesis, enzymes and fine genetic expression. L-methionine is the primary source for SAMe, the universal methyl group donor:
✅ Supports synthesis of phosphatidylcholine and other membrane phospholipids – essential for cell integrity and fluidity
✅ Contributes to creatine production, important for muscle energy reserves (phosphocreatine)
✅ Supports neurotransmitter methylation and neuro-metabolic balance, for clarity and mental tone

• Hepatic detoxification and glutathione – endogenous antioxidant "shield"

The liver is the detoxification center, and glutathione is its main weapon:
✅ L-methionine, through transsulfuration, provides cysteine, the limiting precursor of glutathione (GSH)
✅ GSH neutralizes free radicals and supports hepatic detoxification phases
✅ Contributes to internal biochemical "cleanliness," protecting lipids, proteins and DNA

• Hair, skin and nails – sulfur structures, more resistant

Keratinization and surface tissue resistance depend on disulfide bonds:
✅ L-methionine supports synthesis of keratin and sulfur-rich structural proteins
✅ Contributes to hair with vital appearance, more resistant nails and skin with supported barrier
✅ Favors regeneration of tissues exposed to external factors (heat, pollutants, styling)

• Lipid metabolism and hepatic comfort

Coherent fat metabolism reflects in balanced lipid parameters and liver comfort:
✅ Efficient methylation supports phospholipid synthesis and lipid emulsification
✅ Contributes to fat transport and "packaging" at hepatic level
✅ Integration into balanced lifestyle favors optimal lipid profile

• Cellular energy and performance through creatine

Rapid energy reserves depend on phosphocreatine system:
✅ L-methionine supports guanidinoacetate methylation to creatine
✅ Contributes to energy availability in short, explosive efforts and recovery
✅ Supports energy "coherence" during busy schedule days

• Antioxidant protection and redox balance

Oxidative stress affects membranes and enzymes:
✅ Through glutathione, it supports endogenous antioxidant network
✅ Protects membrane lipids and hemoproteins from oxidation
✅ Favors cellular resilience against daily demands

• Joint comfort and connective tissue

Connective tissues (cartilage, tendons) need sulfur amino acids and correct methylation:
✅ L-methionine participates in structural synthesis and collagen through indirect pathways (methylation, sulfur)
✅ Contributes to mobility and sensation of ease in movements
✅ Supports recovery after daily demands or training

• Acid-base balance and metabolic compatibility

Sulfur amino acids influence metabolic balance fineness:
✅ L-methionine supports buffering and management of metabolic products
✅ Favors coherent integration of proteins and lipids in cellular "economy"
✅ Contributes to general homeostasis, visible in tone and resilience

• Strategic role of Vitamin B-6 (20 mg, 1176%)
B-6 is the enzymatic "screwdriver" of amino acids:
✅ Cofactor for transaminases and methionine-cysteine pathway enzymes
✅ Supports conversions to taurine and glutathione
✅ Contributes to homocysteine metabolism in adequate physiological directions, in network with other methyl donors/acceptors

• Synergy with B network, choline, betaine and minerals

Methylation efficiency is maximal when complementary cofactors exist:
✅ B-6 works in network with B-2, B-12, folate, choline and betaine
✅ Minerals (zinc, magnesium) can support relevant enzymatic activity
✅ Varied diet potentiates structural and antioxidant effects of methionine

• Why L-Methionine 500 mg, Now Foods

• Clear ingredient profile: L-Methionine (Free Form) 1,000 mg + Vitamin B-6 20 mg (1176%) per serving – focused on methylation and transsulfuration
• Free form for efficient metabolic utilization and rapid integration into synthesis
• Now Foods standards: rigorous quality control, traceability and lot-to-lot consistency
• Metabolic versatility: simultaneous support for liver, skin-hair-nails, energy and lipid profile

• Who can benefit from the supplement's qualities?

• Active people who want hepatic detoxification support and antioxidant resilience
• Those concerned about hair, skin and nails, seeking structural support from within
• Sports practitioners or intense lifestyle, interested in rapid energy through creatine synthesis
• Anyone pursuing coherent lipid metabolism and redox balance as foundation of well-being

L-Methionine 500 mg, Now Foods provides the foundation for methylation (SAMe), glutathione and cellular energy, through a powerful pair: L-Methionine (1,000 mg) and Vitamin B-6 (20 mg). This nutritional architecture supports hepatic detoxification, hair-skin-nails, lipid metabolism and antioxidant protection, contributing to coherent body function against daily demands. By integrating into the B cofactor network and through its role in structural and energetic synthesis, L-methionine becomes an essential metabolic "node" for vitality, appearance and performance.



 

Directions for use

Take 2 capsules daily as needed, preferably on an empty stomach. Do not exceed recommended daily dose.



 

Other ingredients

Gelatin (capsule), magnesium stearate (vegetable source) and silica.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Warnings

Do not eat freshness packet. Store in bottle.
Natural color variation may occur in this product.
For adults only. Consult physician if pregnant/nursing, taking medication or have a medical condition. L-methionine may increase blood homocysteine levels in some people. Keep out of reach of children.