DIM 300 mg with BioPerine® – Hormonal Balance, Estrogenic Detoxification and Cellular Health – Advanced Supplement For Regulating Estrogen Metabolism and Supporting Immune Functions

DIM 300 mg, Nutricost is a superior quality dietary supplement, formulated with Diindolylmethane (DIM), a bioactive compound derived from glucosinolates present in cruciferous vegetables such as broccoli, cabbage, cauliflower and kale. DIM is recognized for its ability to support healthy estrogen metabolism, hormonal balance and liver detoxification, thus contributing to the prevention of accumulation of harmful estrogenic metabolites in the body.

The product is enriched with BioPerine® – standardized black pepper extract (Piper nigrum) – which contains minimum 95% piperine, a substance that significantly improves absorption and bioavailability of DIM in the body. This synergistic combination maximizes the efficiency and impact of the supplement on hormonal health, the immune system, cellular balance and natural detoxification processes.

DIM from Nutricost is designed for people who seek to maintain optimal hormonal balance, reduce the effects of excess estrogen, support prostate health, breast and liver health, as well as for those who want efficient functioning of the immune system and advanced cellular protection.

 

Detailed Benefits of DIM (Diindolylmethane) with BioPerine®

 

• Hormonal balance for women and men

DIM is known for its essential role in regulating estrogen metabolism. This process involves converting estrogen into less active and less harmful metabolites for the body, such as 2-hydroxy-estrone, reducing the production of potentially dangerous estrogenic metabolites such as 16-alpha-hydroxy-estrone.

Estrogenic imbalance can occur in both women and men and is associated with:
• Irregular menstrual cycles
• Severe premenstrual syndrome (PMS)
• Difficult menopause and hot flashes
• Hormonal acne and water retention
• Increased abdominal fat accumulation
• Prostate-related problems and decreased testosterone levels

By supporting healthy estrogen metabolism, DIM helps with:
✅ Reducing PMS symptoms and balancing menstrual cycles
✅ Alleviating hot flashes and symptoms associated with menopause
✅ Supporting male hormonal balance by reducing conversion of testosterone to estrogen
✅ Improving mental clarity and mood in fluctuating hormonal contexts

 

• Estrogenic detoxification and improved liver function

The liver is the main organ responsible for metabolizing and eliminating hormones from the body. In the case of slow liver function, active estrogenic metabolites can accumulate and negatively influence hormonal health. DIM supports the liver in the hormonal detoxification process by:

✅ Activating phase II liver detoxification enzymes
✅ Promoting healthy estrogen metabolism through the 2-hydroxy pathway
✅ Reducing oxidative stress at the liver level

This action makes DIM an effective choice for people who have difficulties in properly eliminating estrogens, either as a result of lifestyle, exposure to xenoestrogens (chemicals that mimic estrogen), or genetic causes.

 

• Support for breast, uterine and prostate health

One of the most researched benefits of DIM is related to its positive impact on estrogen-sensitive tissues – especially breasts, uterus and prostate. Excess estrogen or imbalance between estrogen and progesterone/testosterone can lead to abnormal cell proliferation, benign nodules or other changes in these tissues.

DIM can:
✅ Help reduce the risk of benign nodule formation in the breasts or uterus
✅ Support breast tissue health during sensitive hormonal periods (PMS, menopause)
✅ Promote a healthy ratio between testosterone and estrogen among men
✅ Reduce the risk of prostatic inflammation and hypertrophy (BPH)

Through these effects, DIM addresses both women concerned about breast and hormonal health, as well as men who want prostatic protection and optimal hormonal balance.

 

• Antioxidant activity and cellular protection

DIM is not just a hormonal regulator – it also acts as a powerful antioxidant agent and modulator of inflammatory responses. Oxidative stress plays a major role in cellular aging, DNA damage and triggering chronic conditions.

DIM contributes to cellular protection by:
✅ Neutralizing free radicals at the intracellular level
✅ Activating the body's own antioxidant enzymes (e.g., glutathione peroxidase)
✅ Inhibiting inflammatory pathways associated with hormonal imbalances

Thus, this compound supports the maintenance of normal cellular function, reducing the risk of mutations, chronic inflammation and oxidative degradation, which contributes to general well-being and longevity.

 

• Supporting the immune system and cellular balance

In addition to its hormonal benefits, DIM also plays an important role in modulating immune system functions. Studies have shown that DIM positively influences the production of immune cells and contributes to regulating inflammation, making it useful in preventing immune imbalances and maintaining cellular homeostasis.

Immunity benefits include:
✅ Stimulating the production of gamma interferon – essential for antiviral defense
✅ Regulating the activity of NK (natural killer) cells – involved in identifying and eliminating abnormal cells
✅ Modulating the Th1/Th2 balance – supporting an efficient but controlled immune response

This immunomodulatory capacity makes DIM a valuable supplement not only for hormonal balance, but also for strengthening the body's natural defense.

 

• Enhanced bioavailability with BioPerine®

For a supplement to be effective, it must be well absorbed by the body. DIM, in its natural form, may have reduced bioavailability. Nutricost has significantly improved this formula by adding 5 mg of BioPerine® – standardized black pepper extract containing 95% piperine.

BioPerine® is recognized for its ability to:
✅ Increase intestinal absorption of lipophilic nutrients
✅ Slow down initial liver metabolism, allowing higher concentrations of DIM in the blood
✅ Enhance the efficiency of the active ingredient and support prolonged action

This improved formula guarantees that the body benefits from the full therapeutic power of DIM, maximizing the positive effects on hormonal balance and general health.

 

• Support in weight control and body composition

Hormonal imbalances can contribute to weight gain, especially in the abdominal area. Excess estrogen and reduced insulin sensitivity are frequently encountered in metabolic syndrome, polycystic ovaries (PCOS) and menopause.

DIM contributes to:
✅ Reducing water retention and inflammation associated with excess estrogen
✅ Improving insulin sensitivity and balancing glucose metabolism
✅ Supporting body fat burning, especially in perimenopausal women

Through its influence on hormonal and cellular metabolism, DIM helps to reestablish a hormonal profile favorable to weight loss and maintaining a healthy silhouette.

 

Suggested Use

As a dietary supplement, take 1 capsule daily with 8-12 oz of water or as directed by your healthcare professional.



 

Supplement facts
Serving Size: 1 Capsule
Servings Per Container: 120
	Amount Per Serving	%DV
DIM (Diindolylmethane)	300 mg	*
BioPerine® Black Pepper Extract (Piper nigrum)(fruit)(min. 95% piperine)	5 mg	*
*Daily Value (DV) not established.

 

Other Ingredients

Rice flour, hypromellose capsules (cellulose), magnesium stearate (vegetable source), silica.

Manufactured and quality tested in the USA with globally sourced ingredients.

Warnings

For healthy individuals over 18 years of age. Consult a healthcare professional before use if you are pregnant or nursing, taking medication or have a medical condition. Keep out of reach of children. Do not use if the safety seal is broken or missing.

Store in a cool, dry place.