E-400 with Selenium – Synergistic Antioxidants for Heart, Immunity, Skin and Cellular Protection

E-400 with Selenium, Swanson is a dietary supplement designed to offer a powerful combination of vitamin E and selenium, two essential nutrients with major roles in protecting cells against oxidative stress and supporting cardiovascular health, immune system and skin. Each capsule provides 182 mg of vitamin E (as dl-alpha-tocopheryl acetate and d-alpha-tocopherol), equivalent to 1213% of the daily value, together with 50 mcg of selenium (from selenium yeast), covering 91% of the daily requirement.

Vitamin E is one of the most important fat-soluble antioxidants in the body, integrated into cell membrane structure, while selenium is an essential trace mineral, cofactor for key antioxidant enzymes, such as glutathione peroxidase. Together, these two nutrients act synergistically to support cell protection, cardiovascular function, immunity, skin health, eye health and overall body balance.

Detailed benefits of E-400 with Selenium, Swanson

• Advanced antioxidant protection at cellular level

Oxidative stress occurs when free radicals produced naturally in the body exceed the capacity of antioxidant systems to neutralize them. These free radicals can affect lipids in cell membranes, proteins and even DNA. Vitamin E is one of the main fat-soluble antioxidants, inserted in cell membranes, where it acts as a "shield" against lipid peroxidation.

Through the association of 182 mg of vitamin E with 50 mcg of selenium, E-400 with Selenium, Swanson can contribute to:
✅ Neutralizing free radicals and reducing oxidative stress
✅ Protecting cell membranes, especially at the level of lipid-rich tissues (nervous system, skin, cardiovascular system)
✅ Maintaining integrity and optimal cell functioning, in the context of a demanding lifestyle

Selenium, as part of glutathione peroxidase enzymes and other selenoproteins, participates in detoxifying peroxide radicals, complementing vitamin E's role and ensuring a complex antioxidant system.

• Supporting cardiovascular health and circulation

Cardiovascular health is closely linked to oxidative balance and protecting circulating lipids, such as LDL cholesterol, against oxidation. Oxidative stress on lipids can contribute to processes that affect blood vessel walls.

E-400 with Selenium, Swanson can support:
✅ Protecting lipoproteins against oxidation, through vitamin E's antioxidant effect
✅ Maintaining elasticity and normal function of vascular walls
✅ Adjuvant support for healthy circulation, within a balanced lifestyle

Vitamin E can play a role in supporting cell membrane fluidity and circulatory balance, and selenium, through its participation in antioxidant enzymes, helps maintain a vascular environment protected from excess free radicals.

• Supporting the immune system and defense mechanisms

The immune system is very sensitive to the body's antioxidant status. Immune cells (lymphocytes, macrophages) are frequently exposed to free radicals during immune response and need an optimal antioxidant environment to function efficiently.

E-400 with Selenium, Swanson can:
✅ Support normal immune system function, by protecting immune cells from oxidative stress
✅ Support the body's natural defense capacity against external factors
✅ Contribute to maintaining resistance and general vitality, especially during demanding periods

Selenium is known for its role in immune function, being involved in NK (natural killer) cell activity and adaptive immune response. The association with vitamin E amplifies this global effect of supporting natural defense.

• Maintaining skin health and protection against premature aging

Skin is one of the organs most exposed to environmental factors: UV radiation, pollution, temperature variations. The action of these factors generates free radicals, which can accelerate the skin aging process, leading to loss of elasticity, dehydration and wrinkle appearance.

Vitamin E, being a fat-soluble antioxidant, is frequently used in cosmetic products for its protective and moisturizing effects, but internal intake can support skin "from within":
✅ Protecting lipids in the skin layer against peroxidation
✅ Supporting maintenance of a more supple and smoother skin appearance
✅ Contributing to skin protection against oxidative stress associated with environmental exposure

Selenium, through its role in antioxidant enzymes, indirectly participates in maintaining healthy skin tissue, supporting cellular regeneration and oxidative balance.

• Support for ocular function and light-sensitive tissues

Eyes are extremely sensitive to oxidative stress, as exposure to light and oxygen is constant. Retina and other ocular structures contain a high proportion of unsaturated lipids, vulnerable to peroxidation.

Vitamin E in E-400 with Selenium, Swanson:
✅ Helps protect lipids in ocular structures
✅ Supports maintaining integrity of light-sensitive cells
✅ Contributes, in the context of a balanced diet, to maintaining general eye health

The association with selenium consolidates antioxidant defense throughout the body, including at the ocular level, where oxidative stress is constantly present.

• Supporting thyroid function and metabolism, through selenium intake

Selenium is an essential mineral for normal thyroid gland function, being a cofactor for enzymes involved in thyroid hormone conversion (for example, T4 to T3 conversion). Balanced thyroid function contributes to regulating metabolism, energy and body temperature.

Through the content of 50 mcg of selenium, E-400 with Selenium, Swanson can:
✅ Support normal thyroid function
✅ Contribute to maintaining balanced energy metabolism, in the context of a healthy lifestyle
✅ Support overall body balance, especially in modern diet conditions, sometimes poor in selenium

This mineral component excellently complements vitamin E's action, creating a comprehensive support profile for cells and metabolism.

• Supporting energy, vitality and general well-being

A body protected against oxidative stress, with a balanced immune system, supported cardiovascular system and functional thyroid has better premises for maintaining daily energy and vitality.

E-400 with Selenium, Swanson can contribute to:
✅ Supporting a general state of well-being
✅ Maintaining energy levels, through cellular protection and metabolism support
✅ Supporting the body's adaptation to daily stress and environmental factors

Through the combination of vitamin E and selenium, this supplement offers complex support, oriented toward cell protection, optimal functioning of the body's major systems and maintaining long-term internal balance.

Directions for use

As a dietary supplement, take one softgel once or twice daily with food and water.

Other ingredients

Softgel (gelatin, glycerin, purified water), yellow beeswax, soy lecithin. 
Contains soy. 

Warnings

For adults only. Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.
Keep out of reach of children. Do not use if seal is broken. Store in a cool, dry place.