Methyl Folate (5-MTHF Folate) 1,000 mcg: Efficient Methylation, Mental Energy & Cardiometabolic Health – Active Folate with Superior Bioavailability

Methyl Folate, 1,000 mcg, NOW Foods offers biologically active form of folate – (6S)-5-MTHF – provided as Quatrefolic® (glucosamine salt), recognized for stability and high absorption. Label indicates 1,700 mcg DFE (dietary folate equivalents), equivalent of 1,000 mcg 5-MTHF, namely 425% of NRV, to support methylation, homocysteine balance, cognitive function and normal DNA synthesis. Unlike synthetic folic acid, 5-MTHF is ready-to-use form by organism, directly participating in methylation reactions and methionine cycle, with impact on mental energy, mood, immunity and cardiovascular health.

Active folate 5-MTHF plays key role in red blood cell formation, cell division and neurotransmitter production (by donating methyl groups), contributing to clarity and emotional balance. Also, 5-MTHF is involved in homocysteine detoxification by converting it to methionine – important process for blood vessel protection and supporting metabolic efficiency. With Quatrefolic®, NOW Foods ensures modern folate form, soluble, stable and compatible with active lifestyle needs.

Detailed Benefits of Methyl Folate (5-MTHF) 1,000 mcg, NOW Foods

• Efficient methylation & biochemical balance

Methylation is mechanism by which organism transfers methyl groups to "activate" or "deactivate" vital processes – from gene expression to neurotransmitter metabolism. 5-MTHF is essential methyl donor in methionine cycle.

✅ Support for daily methylation processes
✅ Metabolic coherence in demanding periods
✅ Rapid integration into biochemical pathways without additional conversions

• Support for homocysteine balance

Homocysteine is metabolite that, when accumulated, can signal metabolic dysfunctions. 5-MTHF provides methyl for homocysteine transformation into methionine, supporting vascular health.

✅ Maintaining homocysteine in healthy ranges
✅ Cardiovascular comfort associated with good methylation
✅ Synergy with vitamin B12 and B6 in methionine cycle

• Mental energy, clarity & mood

Active folate supports normal synthesis of dopamine, serotonin & norepinephrine, neurotransmitters involved in motivation, concentration and emotional resilience.

✅ Focus in periods with intense cognitive tasks
✅ "Clean" mental energy sensation without agitation
✅ Emotional balance in daily routine

• Normal DNA synthesis & cell division

As cofactor in nucleotide metabolism, 5-MTHF supports correct DNA replication and healthy cell division – fundamental processes for regeneration and tissue balance.

✅ Nutritionally supported genetic integrity
✅ Tissue renewal in physiological rhythm
✅ Cellular level vitality

• Normal red blood cell formation (erythropoiesis)

Folate contributes to erythrocyte production, supporting oxygen transport and exercise endurance. 5-MTHF helps maintain efficient hemopoiesis, essential for tone and clarity.

✅ Support for tissue oxygenation
✅ Vigor in daily activities
✅ Cooperation with vitamin B12 in erythropoiesis

• Superior bioavailability with Quatrefolic®

Glucosamine salt of 5-MTHF (Quatrefolic®) is valued for stability and absorption. Unlike folic acid requiring conversion, 5-MTHF is final form, immediately available.

✅ Efficient absorption, modern delivery profile
✅ Increased stability over time
✅ Reliability in daily use

• Support in periods of increased demands

Stress, intense intellectual tasks or periods of physical remodeling can increase folate need. 5-MTHF helps synergy between protein metabolism, DNA synthesis and neurotransmitter balance.

✅ Adaptive response to daily stress
✅ Metabolic coherence in busy periods
✅ Nutritionally supported recovery and performance

• Compatibility with individual variations

Considering that some people may have genetic differences in folate conversion (e.g. at enzyme level), direct 5-MTHF use can avoid transformation barriers.

✅ Practical approach for active folate support
✅ Variety of nutritional profiles covered
✅ Simplicity: "ready-to-use" form

• Supporting immune system

Folate participates in cell proliferation and new cell formation, important processes for immune response. 5-MTHF supports cell communication and renewal of defense system components.

✅ Nutritionally supported cell rejuvenation
✅ Coherent immune response
✅ Synergy with balanced diet

• Vitality & long-term balance

Through multiple roles, 5-MTHF contributes to more robust homeostasis: energy, mental clarity, balanced mood and vascular protection through homocysteine management.

✅ Visible daily tone
✅ General metabolic comfort
✅ Quality of life supported by intelligent nutrition

• Clear label, efficient dosage

Product offers 1,700 mcg DFE corresponding to 1,000 mcg 5-MTHF, namely 425% NRV, for solid coverage of need.
✅ Suitable concentration for active support
✅ Nutritional information transparency
✅ NOW Foods quality standard

• Why Methyl Folate (5-MTHF) 1,000 mcg, NOW Foods?

• Active folate (6S)-5-MTHF – final metabolic form, ready-to-use;

• Quatrefolic® – glucosamine salt with improved bioavailability & stability;

• Efficient methylation, homocysteine balance and cognitive support;

• Normal DNA synthesis, erythropoiesis and immunity support;

• Clear label: 1,700 mcg DFE = 1,000 mcg 5-MTHF (425% NRV).

Methyl Folate, 1,000 mcg, NOW Foods is modern solution for those wanting metabolic efficiency, mental clarity and vascular protection through truly active folate designed to work in your body's rhythm. With instantly available 5-MTHF, body receives exactly what it needs for coherent methylation, stable energy and balance every day.

Directions for use

Take 1 tablet daily with meal.

Other ingredients

Microcrystalline Cellulose, Stearic Acid (vegetable source) and Silicon Dioxide.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Warnings

For adults only. Elderly persons and those with conditions that may affect vitamin B-12 absorption should frequently check vitamin B-12 status when taking this product, as high doses of folic acid may mask vitamin B-12 deficiency. Consult physician if pregnant/nursing, taking medications (especially phenobarbital, phenytoin, primidone and methotrexate) or have a medical condition (especially any condition involving nutrient malabsorption). Keep out of reach of children.
Store in a cool, dry place after opening.