Life Extension Venotone, Horse Chestnut Extract, Life Extension, 60 capsules

Life Extension
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Expiration Date: 10.2026

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Venotone, Horse Chestnut Extract: Venous Circulation, Leg Comfort, Vascular Tone and Microcirculation Support – Standardized Horse Chestnut Extract in Aescin





Venotone, Horse Chestnut Extract, Life Extension is an advanced dietary supplement formulated to support venous system health and leg comfort, especially in situations where return circulation is stressed. The formula contains horse chestnut extract (Aesculus hippocastanum) from seed, 250 mg, standardized to 20% triterpene glycosides calculated as aescin (equivalent to 50 mg aescin). This standardization is important because aescin is the most studied active fraction of horse chestnut, traditionally associated with support for venous tone, capillary integrity and reduction of unpleasant sensations occurring in the legs.


In modern life, legs are often subjected to constant circulatory stress: many hours standing, prolonged sitting, long trips, high temperatures, sedentarism or abrupt alternations between periods of activity and rest. Under these conditions, sensations of heaviness, leg fatigue, discomfort towards the end of the day or a perception of "loaded legs" may appear. Venous circulation is a system that depends on the tone of vein walls, venous valve function and microcirculation. When these mechanisms are overburdened, the body can benefit from nutritional support oriented towards maintaining comfort and circulatory functionality.


Standardized horse chestnut extract has long been used in formulas for venous health because it supports the balance between capillary permeability and vascular wall resistance, contributing to more efficient microcirculation. In addition, through its action on venous tone, aescin can help maintain a sensation of leg lightness, especially during demanding periods or in warm seasons, when venous discomfort is felt more intensely.




 

Detailed Benefits of Venotone, Horse Chestnut Extract

 

  • Support for Venous Tone and Return Circulation

The venous system has the role of returning blood from the lower limbs towards the heart. This process is influenced by vein elasticity, valve function and the "muscle pump" created by leg movement. When we remain immobile for a long time, blood can stagnate more easily in the lower part of the body, and legs may feel a sensation of pressure or heaviness.


Horse chestnut extract, standardized in aescin, can support:
• venous wall functionality
• maintenance of vascular tone
• leg comfort in the context of circulatory stress


✅ useful on long days at the office or standing
✅ supports sensation of "light" legs
✅ contributes to supporting venous circulation

 

  • Reduction of Heavy and Tired Leg Sensation

End-of-day discomfort is not only due to muscle effort; often it is a combination of fatigue and slowed venous circulation. When microcirculation is overburdened, sensations of "load" and local fatigue can intensify, especially in calves and ankles.


In such situations, the following may appear:
• accentuated evening discomfort
• sensation of tension in calves
• need to elevate legs for relief


Aescin from horse chestnut can help with:
✅ diminishing perception of "heaviness" in the legs
✅ support for comfort during prolonged standing periods
✅ maintaining circulatory well-being throughout the day

  •  Support for Microcirculation and Capillary Resistance

Microcirculation represents the fine network of capillaries that ensures oxygen and nutrient exchanges at tissue level. When capillaries are fragile or when permeability is increased, signs of vascular sensitivity and lower tolerance to mechanical or thermal stress may appear.


Horse chestnut extract is associated with support for:
• capillary integrity
• balance of vascular permeability
• microcirculation resilience


✅ supports more efficient peripheral circulation
✅ contributes to peripheral tissue comfort
✅ supports vascular adaptation to daily stress

 

  • Balance of Vascular Permeability and Local Comfort

One of the important aspects in venous health is how vessel walls manage fluids at tissue level. During periods of heat, after flights or after many hours in the same position, the body may experience local retention and discomfort, and legs may seem more "loaded."


The support offered by aescin is valuable because:
✅ contributes to maintaining comfort under vascular stress conditions
✅ supports local tissue balance
✅ supports better sensation of mobility and lightness

 

  • Comfort During Periods of Travel, Sedentarism or Static Effort

Long trips and sedentarism reduce activation of the calf muscle pump, an essential mechanism for venous return. In addition, static effort (standing for long periods without movement) can accentuate the sensation of leg fatigue, even without intense effort.


Venotone can be relevant for:
• people who work many hours at a desk
• people who stand for long periods (retail, healthcare, services)
• periods of long travel or flights


✅ supports circulatory adaptation in immobility contexts
✅ supports leg comfort at end of day
✅ helps maintain a sensation of freshness

 

  • Support for Active Lifestyle and Functional Recovery

Physical activity is one of the best tools for circulation, but daily schedules don't always allow constant movement. In addition, after training or very active days, legs may feel accentuated fatigue. In these contexts, support for microcirculation and venous tone can contribute to recovering comfort sensation.


Horse chestnut extract can support:
✅ tolerance to daily effort and demanding periods
✅ comfort recovery after active days
✅ maintaining mobility and peripheral well-being

 

  • Standardization in Aescin: Efficiency and Consistency

An important differentiator of the formula is standardization to 20% triterpene glycosides, calculated as aescin. Standardization offers consistency: each serving provides a predictable level of the active fraction, which matters especially for plant extracts where natural variations can be large.


This approach offers:
✅ concentrated extract, with clearly defined active profile
✅ support oriented on the most relevant component (aescin)
✅ formula suitable for consistent use in venous support routine


Venotone, Horse Chestnut Extract, Life Extension is a concentrated formula, built around one of the best-known botanicals for venous health: horse chestnut standardized in aescin. By supporting venous tone, microcirculation and local comfort, the product is suitable for people who wish to support their legs in the context of modern challenges: sedentarism, prolonged standing, travel, heat and intense daily pace.


 

Directions for Use

Read the entire label and carefully follow instructions.
Take one (1) capsule twice daily or as recommended by a healthcare practitioner.



 

Supplement Facts
Serving Size: 1 capsule
  Amount Per Serving % DV
Horse chestnut extract (seed) [std. to 20% (50 mg) triterpene glycosides calculated as aescin] 250 mg **
**Daily Value not established.



 

Other Ingredients

Microcrystalline cellulose, gelatin, maltodextrin, silica, vegetable stearate, hydroxypropyl methylcellulose.




Warnings

Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
Consult your physician if you are undergoing treatment for a medical condition or if you are pregnant or nursing.
Store tightly closed in a cool, dry place.



 
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