Active Methyl Folate with Quatrefolic, 800 mcg – Active Methylation, Cardiovascular Health and Pregnancy and Cognitive Function Support

Active Methyl Folate with Quatrefolic, 800 mcg, Doctor's Best is an advanced supplement with folate in active form, designed to support methylation processes, nervous system health, homocysteine balance, normal blood formation and harmonious development during pregnancy and lactation periods. Each serving provides 800 mcg DFE** of folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt – Quatrefolic®), representing 200% of the daily value for adults and 133% for pregnant or nursing women.

Unlike ordinary folic acid, Quatrefolic® is a form of methylated folate, already active at the cellular level, which means the body no longer needs to transform it through complex enzymatic steps to use it. This is particularly important for people who may have genetic variations (MTHFR type) that limit the conversion of folic acid to its active form. Active Methyl Folate with Quatrefolic provides folate directly in the form the body uses in methylation, DNA synthesis, red blood cell formation and supporting normal fetal development.

Through optimal active folate intake, this supplement contributes to proper nervous system function, emotional balance, homocysteine metabolism and cellular regeneration processes, being suitable for both adults and women in special periods such as preconception, pregnancy or lactation (within recommendations received from a specialist).

Detailed benefits of Active Methyl Folate with Quatrefolic, 800 mcg, Doctor's Best

• Supporting methylation processes and homocysteine balance

Methylation is an essential biochemical process that occurs in every cell, being involved in regulating gene expression, detoxification, neurotransmitter synthesis and homocysteine metabolism. Active folate plays a central role in the methylation cycle, providing methyl groups necessary for these reactions.

When methylation is not optimal, the body may experience:
• disturbances in homocysteine metabolism
• increased oxidative stress
• insufficient support for fine cellular processes

Through the intake of 800 mcg DFE of active folate (Quatrefolic®), the supplement can contribute to:
✅ Supporting the transformation of homocysteine into methionine, helping to maintain normal homocysteine levels
✅ Support for methylation processes involved in DNA synthesis and cellular regeneration
✅ Supporting balanced functioning of metabolism at a deep level

• Cardiovascular health by supporting homocysteine within normal limits

Homocysteine is an intermediate amino acid that, when present in high concentrations, can affect vascular health. Folate, along with other B vitamins, participates in metabolizing homocysteine into less reactive compounds.

Active Methyl Folate with Quatrefolic can support:
✅ Maintaining homocysteine in physiological ranges, by providing folate in directly usable form
✅ Supporting vascular endothelium health
✅ Better supported blood circulation, as part of a balanced lifestyle

Through these mechanisms, active folate indirectly contributes to protecting the cardiovascular system and long-term support of blood vessel health.

• Supporting the nervous system and emotional balance

Folate has an important role in the synthesis of neurotransmitters involved in regulating mood and cognitive functions, such as serotonin, dopamine and noradrenaline. The methylation processes in which folate is involved support the brain in maintaining an adequate neurochemical balance.

Through active folate intake, the body can benefit from:
✅ Supporting central and peripheral nervous system function
✅ Support for emotional balance and psychological well-being
✅ Supporting the ability to adapt to daily stress

Active Methyl Folate can thus be useful for people who want to support neurological functions and general well-being, in a way oriented towards fundamental biochemical processes.

• Supporting cognitive functions and mental clarity

Cognitive functions – attention, memory, information processing speed – depend on neuronal health, neurotransmitter synthesis and DNA structure integrity at the brain level. Active folate is involved in nucleotide synthesis and DNA repair processes, contributing to maintaining neuronal health.

Benefits may include:
✅ Support for mental clarity and concentration
✅ Supporting learning and memory processes
✅ Contributing to maintaining cognitive functions with aging

Through its role in brain metabolism, active folate helps the brain function at optimal parameters, especially in the context of an intellectually demanding lifestyle.

• Normal blood formation and cellular regeneration

Folate is essential for normal DNA synthesis and cell division, critical processes in red blood cell formation and continuous tissue regeneration. Sufficient folate intake helps the body produce healthy blood cells capable of efficiently transporting oxygen.

Active Methyl Folate with Quatrefolic, 800 mcg can support:
✅ Normal red blood cell formation
✅ Regeneration processes at the cellular level
✅ Vitality and physical resistance through supporting tissue oxygenation

Thus, active folate contributes to a general state of energy and proper functioning of the hematological system.

• Supporting pregnancy and lactation periods (normal development and cell division)

Folate is one of the most important vitamins during preconception, pregnancy and lactation periods, due to its role in cell division and normal development of maternal and fetal tissues. The active form, Quatrefolic®, ensures that folate is immediately available for critical growth and cell differentiation processes.

The intake of 800 mcg DFE, which provides 133% of the recommended daily value for pregnant and nursing women, can contribute to:
✅ Supporting normal fetal nervous system development (including in early formation stages)
✅ Support for healthy cell division during intense growth period
✅ Supporting mother's well-being through adequate active folate intake

Active folate is thus a central element of supplementation during special periods of reproductive life, according to recommendations received from a doctor or specialist.

• Advantages of Quatrefolic® active form over ordinary folic acid

Quatrefolic® is a fourth-generation folate form, already methylated ((6S)-5-methyltetrahydrofolate) and bound to glucosamine for superior stability and solubility. Unlike synthetic folic acid, which must be converted in several steps into active folate, Quatrefolic® is directly available in the form used by the body.

This translates into:
✅ Increased bioavailability and efficient absorption
✅ Rapid use by cells in the methylation cycle and DNA synthesis
✅ Special support for people with reduced folic acid conversion (e.g. enzymatic variations)

Through all these effects, Active Methyl Folate with Quatrefolic, 800 mcg, Doctor's Best offers complete support for methylation, cardiovascular health, cognitive functions, normal blood formation and supporting pregnancy and lactation periods, through a modern and efficient form of active folate.

Directions for use

Adult use: Take 1 capsule daily, preferably between meals or as recommended by a nutritionally informed physician.

Other ingredients

Microcrystalline cellulose, hypromellose (vegetarian capsule).

Warnings

Store in a cool, dry place.