AMPK Metabolic Activator controls fat and carbohydrate metabolism through Gynostemma Pentaphyllum and Hesperidin extract, which helps reduce body fat

Inside each of our cells is a key metabolic enzyme called AMPK (adenosine monophosphate-activated protein kinase), which plays a fundamental role in energy homeostasis and acts as a 'lifespan regulator'. AMPK manifests itself in tissues (liver, brain, muscle, bone) where it functions more as a 'metabolic master switch', regulating several intracellular systems. Stimulation of AMPK activity is essential, given what we know about its role in the body.

When AMPK is activated, cells are 'switched' into survival mode and no longer store new fat, instead burning more stored fat - a process similar to calorie restriction.

AMPK Metabolic Activator Life Extension also contains Gynostemma pentaphyllum Extract which plays a role in AMPK activation. Administration of this herb increases glucose consumption through fat burning.

Studies of effects in humans confirmed what most researchers had found in laboratory tests, namely that Gynostemma pentaphyllum stimulates AMPK activity and provides certain longevity benefits.

Metabolic syndrome (MetS) is a condition created by insulin resistance (IR), and includes fat accumulation (especially around the waist), high blood pressure, elevated triglycerides, increased blood sugar (diabetes or pre-diabetes), low "good" cholesterol (HDL). Together, they result in accelerated ageing and an increased risk of cardiac events, coronary heart disease, heart attack, stroke and also an increased risk of diabetes. Unfortunately, most people are not aware of this metabolic disorder.

In one study, participants who took Gynostemma pentaphyllum extract for 12 weeks showed significant reductions in body weight, body mass index (BMI) and body fat percentage compared to the control group. The extract was found to increase energy consumption and fat oxidation while reducing lipid accumulation in adipose tissue.

Another study found that Gynostemma pentaphyllum extract may help reduce appetite and food intake. The extract has been shown to increase levels of the hormone leptin, which is involved in regulating hunger and satiety, while reducing levels of the appetite-stimulating hormone ghrelin.







AMP-activated protein kinase (AMPK) is an enzyme that plays a crucial role in cellular energy metabolism. It is activated when cellular energy levels are low, such as during exercise or fasting, and helps maintain energy homeostasis by promoting energy-producing pathways and inhibiting energy-consuming pathways.


 

Here are some key facts about AMPK Metabolic Activator:

 

• Metabolism regulation:

AMPK is a key regulator of cellular energy metabolism. It is activated in response to energy stress, such as during exercise or fasting, and helps maintain energy homeostasis by promoting energy-producing pathways and inhibiting energy-consuming pathways. AMPK accomplishes this by phosphorylating and activating enzymes that promote glucose uptake and oxidation, such as GLUT4 and hexokinase, while inhibiting enzymes that promote glucose production, such as gluconeogenic enzymes. AMPK also promotes fatty acid oxidation by phosphorylating and activating enzymes involved in beta-oxidation, while inhibiting enzymes involved in fatty acid synthesis, such as acetyl-CoA carboxylase.
 

• Effects on appetite and weight:

AMPK may also have effects on appetite and weight regulation. It has been shown to increase energy intake and reduce food consumption, leading to weight loss. One of the ways AMPK achieves this is by activating the hypothalamus, which is the part of the brain that controls appetite and satiety. AMPK also inhibits the production of ghrelin, the hormone that stimulates appetite, and stimulates the production of leptin, the satiety hormone.
 

• Role in exercise:

AMPK is activated during exercise and helps increase glucose uptake and fatty acid oxidation in skeletal muscle. It is thought to be an important mediator of metabolic adaptations to exercise. AMPK activation during exercise leads to an increase in mitochondrial biogenesis, which helps to increase energy production and reduce oxidative stress.
 

• Effects on ageing:

AMPK has been implicated in the regulation of aging and age-related diseases. It has been shown to promote cellular and body health by increasing mitochondrial function, reducing inflammation and promoting autophagy (the process by which cells break down and recycle damaged or dysfunctional components). AMPK activation has been shown to extend lifespan and may help delay the onset of age-related diseases such as Alzheimer's and Parkinson's.
 

• Drug targeting:

Because of its important role in cellular metabolism and energy homeostasis, AMPK is a drug target for the treatment of metabolic disorders such as type 2 diabetes and obesity. Metformin, one of the most commonly prescribed drugs for type 2 diabetes, works by activating AMPK. Other drugs, such as AICAR and A-769662, directly activate AMPK and may have potential therapeutic benefits for metabolic disorders.


 

What are the benefits of AMPK Metabolic Activator?

 

• Contributes to gradual weight loss by eliminating excess body fat.
• Recommended for pre-diabetes, diabetes, obesity, cardiovascular disease, ageing.
• Plays a fundamental role in energy homeostasis and acts as a "life span regulator".
• Lowers blood sugar levels by increasing cellular glucose uptake.
• Increases the number of new and healthy mitochondria.
• Lowers triglyceride levels in the blood.
• Reduces insulin resistance.
• Combats liver degeneration.

 

Suggestions for use

Read the entire label and follow the instructions carefully before use.

Take one (1) tablet daily or as recommended by a healthcare professional.






 

Other ingredients

Microcrystalline cellulose, stearic acid, croscarmellose sodium, hydroxypropyl cellulose, aqueous coating (hypromellose, glycerine, purified water), silica, vegetable stearate.
 

Warnings

Keep out of reach of children.
Do not exceed recommended dose.
Do not buy if outer seal is broken or damaged.
When using nutritional supplements, please consult your doctor if you are undergoing treatment for a medical condition or if you are pregnant or breastfeeding.
Keep tightly closed in a cool, dry place.