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  4. PEA400, (Palmitoylethanolamide), 400 mg, Natural Factors, 90 capsules

Natural Factors PEA400, (Palmitoylethanolamide), 400 mg, Natural Factors, 90 capsules

Natural Factors
-31%
166,65 RON 114,99 RON

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Expiration Date: 04.2028

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PEA400, Palmitoylethanolamide: Natural Support for Inflammation, Neuropathic Pain & Immune Balance – Advanced Supplement for Nervous System and Tissue Health

 

PEA400, 400 mg, Natural Factors is a high-quality dietary supplement containing Palmitoylethanolamide (PEA), a natural compound present in the body and some foods, essential for regulating inflammation, managing chronic pain and supporting nervous system balance. Palmitoylethanolamide is an endogenous fatty acid amide, naturally biosynthesized in response to inflammation, cellular stress or trauma.

 

Its anti-inflammatory and neuroprotective actions have been demonstrated in numerous clinical studies, being widely used for alleviating neuropathic pain, fibromyalgia, chronic inflammation and immune disorders. Formulated from safflower oil – a natural source of essential fatty acids – the PEA400 product provides high bioavailability and efficient absorption.

 

PEA supplementation is a safe and effective therapeutic option for individuals suffering from inflammatory conditions, chronic pain, nerve sensitivity or immune system dysfunction. Through its complex actions, PEA supports cellular health, nervous and immune system function, actively contributing to maintaining optimal physiological balance.

Detailed Benefits of Palmitoylethanolamide (PEA)

🛡️ Reduction of chronic and acute inflammation

Inflammation is a natural defense mechanism of the body, but when it becomes chronic, it can lead to tissue damage, persistent pain and degenerative diseases. PEA acts as a pro-homeostatic mediator that regulates the release of pro-inflammatory cytokines, balancing the immune response without suppressing the body's natural defense.

✅ inhibition of mast cell activation involved in inflammatory and allergic responses
✅ decrease in inflammatory cytokine production
✅ modulation of PPAR-α receptors, which regulate inflammation and lipid metabolism

🧠 Alleviation of neuropathic and chronic pain

Neuropathic pain is often difficult to treat and results from damage to peripheral nerves or the central nervous system. It is encountered in conditions such as sciatica, carpal tunnel syndrome, fibromyalgia, multiple sclerosis or post-surgical pain. PEA is recognized as a natural analgesic that targets the cause of pain – neurogenic inflammation.

✅ regulation of microglial activity involved in chronic pain
✅ reduction of nerve hypersensitivity by stabilizing neuronal membranes
✅ relief of chronic pain without psychoactive effects

♻️ Immune system balance support

PEA is a natural modulator of the immune system, acting without compromising the body's defense function. In the context of autoimmune diseases, allergies or recurrent inflammation, PEA helps reduce excessive immune reactions and associated oxidative stress.

✅ inhibition of excessive activation of immune cells
✅ reduction of inflammatory mediator release during allergic reactions
✅ contribution to balancing the neuro-immuno-endocrine axis

✨ Neuroprotection and cognitive function support

Palmitoylethanolamide plays an essential role in maintaining neuronal health, protecting nerve cells from oxidative stress, inflammation and excitotoxicity. Preclinical and clinical studies indicate that PEA can support memory, focus and mental clarity, especially under conditions of neuroinflammatory stress or aging.

✅ stabilization of neuronal homeostasis against oxidative stress and inflammation
✅ reduction of microglial activation
✅ enhancement of endocannabinoid action involved in neuroplasticity

💪 Muscle and tissue health support

Localized inflammation in muscle and connective tissues is a common factor in muscle pain, tendinitis and chronic overuse. PEA reduces muscle discomfort through mechanisms similar to those observed in the nervous system – reducing inflammation, improving local circulation and calming the nociceptive response.

✅ reduction of swelling and inflammation in injured areas
✅ alleviation of muscle pain and post-exertion stiffness
✅ faster recovery after physical exertion or minor injuries

🌿 Excellent tolerance and increased bioavailability

A significant advantage of PEA is its favorable safety profile. Being an endogenous compound, PEA is well-tolerated even with long-term use. It causes no sedation, does not interfere with cognitive functions and does not induce dependence. The form used in the PEA400 product, derived from safflower oil, ensures efficient absorption and long-term stability.

✅ endogenous compound, well-tolerated for long-term use
✅ no sedation and no dependence risk
✅ efficient absorption through the safflower oil-derived form

Whether used for pain management, inflammation reduction or cognitive function support, PEA400 is a valuable ally for anyone seeking natural, effective and safe solutions, contributing to cellular health, nervous and immune system function and maintaining optimal physiological balance.

Key Advantages

400 mg Palmitoylethanolamide (PEA) Source from safflower oil Support for inflammation and neuropathic pain Supports nervous system and immune balance Vegetarian formula, free of animal products
Nutritional Information
Serving size: 1 capsule
  Amount per serving % NRV
Palmitoylethanolamide (PEA)
(safflower oil) (seeds)		 400 mg **
** Daily value not established.

Directions for Use

Take 1 capsule 1-3 times daily or as directed by a healthcare practitioner.

Key Advantages

400 mg Palmitoylethanolamide (PEA) Source from safflower oil Support for inflammation and neuropathic pain Supports nervous system and immune balance Vegetarian formula, free of animal products

Other Ingredients

Microcrystalline cellulose, vegetarian capsule (carbohydrate gum [cellulose], purified water), magnesium stearate (vegetable grade), stearic acid, silica.
Free of artificial colours, preservatives or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, nuts or GMOs.
Manufactured by Natural Factors to ensure safety and potency in accordance with GMP practices of FDA & Health Canada.

Warnings

As with any supplement, consult your physician before use if you are pregnant, nursing or trying to conceive, or if you are taking medications, have a medical condition, or anticipate surgical intervention. Keep out of reach of children.
Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

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