Transform your health and wellness with pyridoxal-5-phosphate (P-5-P) - The clinically proven active form of vitamin B6 that delivers a host of powerful benefits

Pyridoxal-5-phosphate (P-5-P) is the active coenzyme form of vitamin B6, which is a water-soluble vitamin essential for many important functions in the body. Vitamin B6 is involved in over 100 enzymatic reactions, including amino acid metabolism, neurotransmitter production and haemoglobin synthesis.

P-5-P is the biologically active form of vitamin B6, which is used directly by the body, without requiring conversion by the liver. This is in contrast to other forms of vitamin B6, such as pyridoxine and pyridoxamine, which must be converted to P-5-P before they can be used. As a result, P-5-P is considered the most bioavailable form of vitamin B6.

P-5-P is particularly important for people with deficient vitamin B6 metabolism, including the elderly and those with genetic variations that affect vitamin B6 conversion. These individuals may not be able to efficiently convert other forms of vitamin B6 to P-5-P, making P-5-P supplementation more beneficial.

Research has shown that P-5-P may have a number of potential health benefits. For example, it may help reduce inflammation, support cardiovascular health, improve cognitive function and promote a healthy mood. P-5-P may also be beneficial for people with certain health conditions such as autism spectrum disorder, premenstrual syndrome (PMS) and carpal tunnel syndrome.



 

P-5-P Benefits

 

• Supports cognitive function:

P-5-P is involved in the production of several neurotransmitters, including serotonin and dopamine, which play important roles in mood regulation and cognitive function. Low levels of vitamin B6 have been associated with cognitive decline, and P-5-P supplementation may help improve cognitive function and memory. For example, a study published in the journal Nutrients found that P-5-P supplementation improved memory performance in healthy adults.
 

• Reduces inflammation:

P-5-P has been shown to have anti-inflammatory properties, which may help reduce inflammation and pain associated with conditions such as rheumatoid arthritis. Inflammation is a common factor underlying many chronic diseases, and reducing inflammation can have a positive impact on overall health. A study published in the journal Annals of the Rheumatic Diseases found that P-5-P supplementation reduced disease activity in patients with rheumatoid arthritis.
 

• Supports cardiovascular health:

P-5-P may help reduce homocysteine levels, which is a risk factor for cardiovascular disease. Homocysteine is an amino acid that can cause damage to blood vessels and increase the risk of heart disease. P-5-P may also help improve lipid profile, including reducing triglycerides and LDL cholesterol. A study published in the American Journal of Clinical Nutrition found that P-5-P supplementation reduced triglyceride levels in patients with type 2 diabetes.
 

• Promotes healthy mood:

P-5-P is involved in the production of serotonin and GABA, neurotransmitters that are important for mood regulation. Studies have suggested that P-5-P supplementation may help improve mood and reduce symptoms of depression. For example, a study published in the journal Psychopharmacology found that P-5-P supplementation improved mood in healthy adults.
 

• Supports immune function:

P-5-P is important for immune function, including antibody production and T-cell activation. It may help boost the immune system and protect against infection. A study published in the Journal of Nutritional Biochemistry found that P-5-P supplementation improved immune function in older adults.
 

• It may relieve symptoms of PMS:

P-5-P supplementation has been shown to help reduce symptoms of premenstrual syndrome (PMS), including mood swings, bloating and breast tenderness. A study published in the Journal of Women's Health found that P-5-P supplementation reduced PMS symptoms in women.
 

• It may improve carpal tunnel syndrome:

P-5-P supplementation may help relieve symptoms of carpal tunnel syndrome, including pain, numbness and tingling in the hands and wrists. A study published in the Journal of Orthopaedic Science found that P-5-P supplementation improved carpal tunnel syndrome symptoms in patients.



 

Suggested use

 As a dietary supplement, take one capsule per day with water.

 

Other ingredients

Rice flour, gelatin, magnesium stearate.

 

Warnings

For adults only. Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children. Do not use if seal is broken. Store in a cool, dry place.